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OCR: s an The standard clinical dose administered Transient intravenous bolus injection is 200-500ug and mild nausea, a sense of urinary urgency, bod moderate (rarely marked) increases in bl The surge pressure occur as side effects of injection leads to a of TSH release induced by TRH injection e (T3) and detectable rise in plasma triiodothyronir , although also an increase in thyroxine (T4) release e reflected the latter is usually not large enough to els of T4. in a significant increase in circulating le SH A striking feature of the TRH-induced T fior response is that its effects are blocked by L the treatment with thyroid hormone. Indee Is of interaction of the negative feedback effe he thyroid hormone on the pituitary with t ment in thestimulating effects of TRH is a major ele feedback cont ...